Leaflet RAPAMUNE 1mg / ml oral solution
Indicated for: prevention of transplant rejection
Route of administration: oral
Substance: sirolimus (immunosuppressant)
ATC: L04AA10 (Antineoplastic and immunomodulating agents | Immunosuppressants | Selective immunosuppressants)
Avoid grapefruit and grapefruit juice.
Avoid live vaccines during treatment if contraindicated.
This medicine may increase the risk of infections.
This medicine may have important interactions with other medicines.
Use during breastfeeding only on medical advice.
Use during pregnancy only on medical advice.
Sirolimus, also known as rapamycin, is an immunosuppressive agent primarily used to prevent organ rejection following renal transplantation. It works by inhibiting the mTOR (mammalian target of rapamycin) pathway, reducing T and B lymphocyte proliferation and suppressing the immune response.
Sirolimus is administered orally, usually once daily, and is used in combination with other immunosuppressive medications such as cyclosporine and corticosteroids. It is indicated for patients requiring prevention of acute organ rejection or those who cannot tolerate other immunosuppressive therapies.
Common side effects include hyperlipidemia, hypertension, anemia, thrombocytopenia, and infections. In rare cases, severe adverse reactions such as interstitial pneumonitis or renal function impairment may occur. Regular monitoring of hematological and metabolic parameters is essential during treatment.
Sirolimus is an effective therapeutic option for patients undergoing organ transplantation, contributing to prolonged graft survival and reduced risk of rejection.
General data about RAPAMUNE 1mg / ml
- Substance: sirolimus
- Date of latest medicines list: 01-07-2015
- Product code: W61482001
- Concentration: 1mg / ml
- Pharmaceutical form: oral solution
- Quantity: 1
- Product type: Original
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for sirolimus
Concentrations available for sirolimus
- 1mg
- 1mg/ml
- 2mg
- 5mg