Active substance
Results for the substance remibrutinib
1 result
About this active substance
Remibrutinib is a medicine used in adults with chronic spontaneous urticaria, a condition with recurring hives, itching and sometimes swelling that occurs without a clear trigger and lasts for more than six weeks. It is used when H1 antihistamines have not controlled symptoms well enough.
The medicine blocks Bruton’s tyrosine kinase (BTK), an enzyme involved in activating cells that release histamine and other inflammatory substances. By reducing this signalling, remibrutinib can decrease itching, wheals and swelling. It is not an emergency treatment for anaphylaxis, so patients with severe allergic reactions should follow their prescribed emergency plan.
Remibrutinib is taken by mouth as tablets, usually twice daily. Treatment may be long term, but the doctor will reassess the benefit regularly and may stop it if there is not enough improvement after several months. Swallow the tablets as instructed and do not crush them or change the dose without medical advice.
Possible side effects include upper respiratory tract infections, common cold or flu-like illness, headache, nausea, abdominal or back pain and fever. Bruising, bleeding and herpes virus infections may occur. Tell your doctor if you take blood thinners, have liver problems, are due for surgery, are pregnant or planning pregnancy, or are breastfeeding.
The medicine blocks Bruton’s tyrosine kinase (BTK), an enzyme involved in activating cells that release histamine and other inflammatory substances. By reducing this signalling, remibrutinib can decrease itching, wheals and swelling. It is not an emergency treatment for anaphylaxis, so patients with severe allergic reactions should follow their prescribed emergency plan.
Remibrutinib is taken by mouth as tablets, usually twice daily. Treatment may be long term, but the doctor will reassess the benefit regularly and may stop it if there is not enough improvement after several months. Swallow the tablets as instructed and do not crush them or change the dose without medical advice.
Possible side effects include upper respiratory tract infections, common cold or flu-like illness, headache, nausea, abdominal or back pain and fever. Bruising, bleeding and herpes virus infections may occur. Tell your doctor if you take blood thinners, have liver problems, are due for surgery, are pregnant or planning pregnancy, or are breastfeeding.