Medication leaflets

Active substance

Results for the substance terbinafine

20 results

About this active substance

Terbinafine is an antifungal medicine used for dermatophyte infections of the skin, nails or scalp, depending on the form. It may be used locally as a gel, cream or spray for skin fungal infections, while tablets are mainly used for nail infections or more extensive disease. It works by blocking ergosterol synthesis, which fungi need for their cell membranes.

Topical forms are applied to clean, dry skin for the recommended duration, even if symptoms improve quickly. Tablets are taken by mouth only when prescribed, because treatment may last weeks or months. In nail infections, improvement is slow because the healthy nail must grow out. Oral treatment should not be used without a correct diagnosis.

Side effects may include local irritation, itching or stinging with skin forms. Tablets may cause nausea, diarrhoea, abdominal pain, headache, rash, muscle pain, changes in taste or smell and, rarely, serious liver injury. The doctor may recommend liver tests before and during treatment.

Stop treatment and contact a doctor urgently if jaundice, dark urine, persistent nausea, severe tiredness, abdominal pain, widespread rash, fever or allergic reactions occur. Tell the doctor about liver disease, kidney disease, pregnancy, breastfeeding and all medicines used. Local hygiene, keeping skin dry and changing footwear can help prevent recurrence.