Leaflet XIDOFA 500mg / 20mg modified release tablets

Product code:
W72099001
Quantity:
10
Indicated for:
pain and inflammation
Route of administration:
oral
Substance:
naproxen + esomeprazole (nonsteroidal anti-inflammatory drug+proton pump inhibitor)
ATC
M01AE52 — Musculo-skeletal system | Antiinflammatory and antirheumatic products | Antiinflammatory and antirheumatic products, non-steroids | Propionic acid derivatives
Naproxen + esomeprazole is a combination medication used to treat pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, while reducing the risk of gastrointestinal complications caused by nonsteroidal anti-inflammatory drugs (NSAIDs).

- Naproxen is an NSAID that reduces pain, inflammation, and fever by inhibiting prostaglandin production.
- Esomeprazole is a proton pump inhibitor (PPI) that decreases stomach acid production, protecting the stomach lining from irritation and ulcers caused by naproxen.

This combination is particularly indicated for patients at higher risk of gastric ulcers or gastrointestinal bleeding.

Side effects may include nausea, stomach pain, diarrhea, dizziness, or, in rare cases, allergic reactions. Long-term use may increase the risk of cardiovascular events (due to naproxen) or gastrointestinal infections (due to reduced stomach acid). It is important to take this medication as prescribed by a doctor.

General data about XIDOFA 500mg / 20mg

Substance:
naproxen + esomeprazole
Date of latest medicines list:
01-09-2026
Product code:
W72099001
Concentration:
500mg / 20mg
Pharmaceutical form:
modified release tablets
Quantity:
10
Product type:
Generic medicine
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
MSN LABS EUROPE LIMITED - MALTA
Holder:
MSN LABS EUROPE LIMITED - MALTA
Number:
16769/2026/01
Shelf life:
18 months

Precautions:

Photosensitivity

Avoid excessive exposure to sunlight or UV radiation.

Major drug interactions

This medicine may have important interactions with other medicines.

Nephrotoxicity

This medicine may affect the kidneys.

Pregnancy warning

Use during pregnancy only on medical advice.

Bleeding risk

This medicine may increase the risk of bleeding.

Ulcer / gastrointestinal bleeding

This medicine may increase the risk of ulcer or gastrointestinal bleeding.