Leaflet SIOFOR 1000mg prolonged-release tablets


Indicated for: type 2 diabetes mellitus

Substance: metformin (biguanide antidiabetic)

ATC: A10BA02 (Alimentary tract and metabolism | Blood glucose lowering drugs, excl. insulins | Biguanides)

Metformin is a medication primarily used to treat type 2 diabetes. It is an oral antidiabetic from the biguanide class that helps lower blood glucose levels by improving insulin sensitivity and reducing glucose production by the liver. Metformin also slows the absorption of glucose from the digestive tract.

This medication is commonly used as a first-line treatment for type 2 diabetes, especially in overweight or obese patients, as it does not cause weight gain. In some cases, it is also used for polycystic ovary syndrome (PCOS) due to its effects on glucose and insulin metabolism.

Side effects may include nausea, diarrhea, abdominal pain, or loss of appetite, particularly at the start of treatment. In rare cases, it can cause lactic acidosis, a serious complication, especially in patients with kidney impairment or other severe conditions. It is important to take metformin as prescribed by a doctor, with regular monitoring of kidney function.

SIOFOR 1000mg prolonged-release tablets BERLIN CHEMIE, metformin

General data about SIOFOR 1000mg

  • Substance: metformin
  • Date of last drug list: 01-05-2026
  • Commercial code: W65730002
  • Concentration: 1000mg
  • Pharmaceutical form: prolonged-release tablets
  • Quantity: 30
  • Product type: generic
  • Price: 24.91 RON
  • Prescription restrictions: P-6L - Medicines prescription that isn't retained in the pharmacy (can be renewed); the prescription can be used for 6 months from the moment of release.

Marketing authorisation

  • Manufacturer: BERLIN - CHEMIE AG - GERMANIA
  • Holder: BERLIN - CHEMIE AG - GERMANIA
  • Number: 11415/2019/02
  • Shelf life: 3 years

Pharmaceutical forms available for metformin

Concentrations available for metformin

  • 1000mg
  • 500mg
  • 750mg
  • 850mg

Compensation lists for SIOFOR 1000mg Berlin Chemie

NHP 5 (C2) - Diabetes

Price

Copayment

Patient

24.91 RON

4.70 RON

20.21 RON