Active substance

Results for the substance canagliflozin metformin

4 results

About this active substance

Canagliflozin and metformin are used together for the treatment of type 2 diabetes, providing more effective blood sugar control. This combination combines the effects of the SGLT2 inhibitor (canagliflozin) and the biguanide (metformin).

Canagliflozin reduces glucose reabsorption in the kidneys, eliminating excess glucose through urine, while metformin decreases glucose production in the liver and improves insulin sensitivity.

The medication is taken orally, usually twice daily, with meals to reduce the risk of gastrointestinal side effects. It is important to follow the doctor's instructions and monitor blood sugar levels.

Side effects may include nausea, diarrhea, urinary tract infections, or, in rare cases, diabetic ketoacidosis or lactic acidosis. Patients should inform their doctor of any unusual symptoms.