Leaflet ROBINUL-NEOSTIGMINE 0.5mg / ml 2.5mg / ml solution for injection

Indicated for: reversal of neuromuscular blockade

Route of administration: injectable

Substance: glycopyrronium bromide + neostigmine methylsulfate (antimuscarinic + cholinesterase inhibitor)

ATC: A03AB02 (Alimentary tract and metabolism | Drugs for functional gastrointestinal disorders | Synthetic anticholinergics, quaternary ammonium compounds)

Precautions:
Glaucoma warning
Glaucoma warning

Use caution if you have glaucoma or increased eye pressure.

Anticholinergic effects
Anticholinergic effects

May cause dry mouth, constipation, urinary retention, or blurred vision.

Elderly warning
Elderly warning

Older people may have an increased risk of side effects.

Glycopyrronium bromide + neostigmine methylsulfate is a combination of medications used to reverse the effects of muscle relaxants administered during surgery. It helps restore normal muscle function after general anesthesia.

Glycopyrronium bromide is an anticholinergic agent that reduces side effects such as excessive secretions or bradycardia (slowed heart rate) caused by neostigmine. Neostigmine methylsulfate is a cholinesterase inhibitor that increases acetylcholine levels, aiding in the restoration of muscle contraction.

This combination is effective and well-tolerated but may cause side effects such as dry mouth, nausea, dizziness, or changes in heart rate. It is important for the medication to be administered under strict medical supervision, usually in a hospital setting.

General data about ROBINUL-NEOSTIGMINE 0.5mg / ml 2.5mg / ml

  • Substance: glycopyrronium bromide + neostigmine methylsulfate
  • Date of latest medicines list: 01-12-2025
  • Product code: W69292001
  • Concentration: 0.5mg / ml 2.5mg / ml
  • Pharmaceutical form: solution for injection
  • Quantity: 10
  • Product type: Generic medicine
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: EUMEDICA PHARMACEUTICALS GMBH - GERMANIA
  • Holder: CN UNIFARM S.A. - ROMANIA
  • Number: 765/2022/01