Leaflet RANTUDIL RETARD 90mg modified release capsules
Indicated for: pain and inflammation
Route of administration: oral
Substance: acemetacin (nonsteroidal anti-inflammatory drug)
ATC: M01AB11 (Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Acetic acid derivatives and related substances)
This medicine may have important interactions with other medicines.
This medicine may affect the kidneys.
Use during pregnancy only on medical advice.
This medicine may increase the risk of bleeding.
This medicine may increase the risk of ulcer or gastrointestinal bleeding.
Acemetacin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with rheumatic and musculoskeletal conditions. It is a derivative of indomethacin but has better gastrointestinal tolerability. Acemetacin is indicated for conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, post-traumatic or post-operative pain, and other inflammatory disorders.
It works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins, substances involved in inflammation, pain, and fever.
The medication is taken orally, usually in the form of capsules or tablets, and the dosage is adjusted based on the severity of symptoms and the patient's response. In some cases, it may be used as suppositories to minimize gastrointestinal irritation.
Common side effects include gastrointestinal disturbances such as nausea, abdominal pain, diarrhea, or constipation. Rarely, more severe reactions such as gastric ulcers, gastrointestinal bleeding, allergic reactions, or kidney impairment may occur.
Acemetacin should be used with caution in patients with a history of gastric ulcers, renal insufficiency, hypertension, or cardiovascular diseases. It is also important to avoid concurrent use with other NSAIDs or anticoagulants, as this may increase the risk of bleeding.
General data about RANTUDIL RETARD 90mg
- Substance: acemetacin
- Date of latest medicines list: 01-01-2014
- Product code: W00007001
- Concentration: 90mg
- Pharmaceutical form: modified release capsules
- Quantity: 20
- Product type: Original
- Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.
Pharmaceutical forms available for acemetacin
Concentrations available for acemetacin
- 60mg
- 90mg