Take with food
Take this medicine with food.
Medicine information PYLERA 140mg / 125mg / 125mg capsules
- Product code:
- W72178001
- Quantity:
- 120
- Indicated for:
- Helicobacter pylori eradication with omeprazole and prevention of recurrence of associated peptic ulcer disease
- Route of administration:
- oral
- Substance:
- bismuth subcitrate + metronidazole + tetracycline (bismuth compound+nitroimidazole antibacterial+tetracycline antibacterial)
- ATC
- A02BD08 — Alimentary tract and metabolism | Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord) | Combinations for eradication of helicobacter pylori
Bismuth subcitrate + metronidazole + tetracycline is used in adults to eradicate Helicobacter pylori, a bacterium associated with stomach and duodenal ulcers. Bismuth and the two antibiotics act together against the organism. Treatment is combined with omeprazole, which reduces stomach acid and supports ulcer healing.
Take the capsules in divided doses after meals and at bedtime, usually for 10 days, as prescribed. Swallow them whole with a large glass of water and do not lie down immediately afterwards. Do not take them at the same time as dairy products, antacids, iron or zinc supplements. Complete the course and do not double missed doses.
Possible side effects include nausea, diarrhoea, abdominal pain, metallic taste and darkening of stools or the tongue. Bismuth-related colouring is usually harmless, but black stools with weakness or dizziness need assessment. Avoid intense sunlight. Severe diarrhoea, persistent tingling or blistering rashes require prompt medical advice.
Avoid alcohol during treatment and afterwards for the period stated in the leaflet. The combination is contraindicated during pregnancy and breastfeeding and in kidney or liver impairment. Tell the doctor if you take anticoagulants, lithium or retinoids. Breathing difficulty, facial swelling or vomiting blood requires urgent help.
Take the capsules in divided doses after meals and at bedtime, usually for 10 days, as prescribed. Swallow them whole with a large glass of water and do not lie down immediately afterwards. Do not take them at the same time as dairy products, antacids, iron or zinc supplements. Complete the course and do not double missed doses.
Possible side effects include nausea, diarrhoea, abdominal pain, metallic taste and darkening of stools or the tongue. Bismuth-related colouring is usually harmless, but black stools with weakness or dizziness need assessment. Avoid intense sunlight. Severe diarrhoea, persistent tingling or blistering rashes require prompt medical advice.
Avoid alcohol during treatment and afterwards for the period stated in the leaflet. The combination is contraindicated during pregnancy and breastfeeding and in kidney or liver impairment. Tell the doctor if you take anticoagulants, lithium or retinoids. Breathing difficulty, facial swelling or vomiting blood requires urgent help.
General data about PYLERA 140mg / 125mg / 125mg
- Substance:
- bismuth subcitrate + metronidazole + tetracycline
- Date of latest medicines list:
- 01-10-2026
- Product code:
- W72178001
- Strength:
- 140mg / 125mg / 125mg
- Pharmaceutical form:
- capsules
- Quantity:
- 120
- Product type:
- Original
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Official documents
Warnings:
Driving impairment
This medicine may affect your ability to drive or use machines.
General warning
Read the package leaflet before use.
Colitis / severe diarrhea
Seek medical advice if severe or persistent diarrhea occurs.
Contraindicated during breastfeeding
Do not use this medicine while breastfeeding.
Contraindicated during pregnancy
Do not use this medicine during pregnancy.
Contraindicated in children
Do not give to children for whom it is contraindicated.
Avoid alcohol
Avoid alcohol during treatment.
Avoid milk, calcium, iron, or antacids
Do not take with milk, calcium, iron, magnesium, or antacids if separation is recommended.
Photosensitivity
Avoid excessive exposure to sunlight or UV radiation.
Hepatotoxicity
This medicine may affect the liver.
Major drug interactions
This medicine may have important interactions with other medicines.
Neuropathy / neurotoxicity
This medicine may affect the nerves or nervous system.
Do not split / crush / chew
Do not split, crush, or chew this medicine.
Severe skin reactions
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Cardiac risk / QT prolongation / arrhythmias
This medicine may increase the risk of heart rhythm disturbances.
Seizure risk
This medicine may increase the risk of seizures.
Vision disturbances
This medicine may cause vision disturbances.