Medicine information PERGOVERIS (450UI+225 UI)/0.72ml solution for injection in pre-filled pen

Product code:
W65140001
Quantity:
1
Indicated for:
infertility
Route of administration:
injectable
Substance:
follitropin alfa + lutropin alfa (gonadotropins)
ATC
G03GA30 — Genito urinary system and sex hormones | Gonadotropins and other ovulation stimulants
Follitropin alfa and lutropin alfa are two recombinant hormones used together in fertility treatments to stimulate the ovaries in women with ovarian insufficiency or poor response to stimulation. Follitropin alfa stimulates follicle development, while lutropin alfa (luteinizing hormone) supports oocyte maturation and ovulation.

They are administered by subcutaneous injection, following a personalized protocol set by the fertility specialist. The dose and duration of treatment are adjusted based on individual response and ultrasound and hormonal monitoring. Strict adherence to medical instructions is essential for therapy success.

Side effects may include injection site reactions, bloating, headaches, abdominal discomfort, or, more rarely, ovarian hyperstimulation syndrome. Allergic reactions or mood changes may also occur and should be reported to the doctor.

The combination of follitropin alfa and lutropin alfa provides an effective solution for women with complex fertility issues, but the treatment requires close medical supervision to prevent complications and ensure the best outcomes.

General data about PERGOVERIS (450UI+225 UI)/0.72ml

Substance:
follitropin alfa + lutropin alfa
Date of latest medicines list:
01-10-2026
Product code:
W65140001
Strength:
(450UI+225UI) / 0.72ml
Pharmaceutical form:
solution for injection in pre-filled pen
Quantity:
1
Product type:
Original
Price:
1010.12 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
MERCK SERONO S.P.A. - ITALIA
Holder:
MERCK EUROPE B.V. - OLANDA
Number:
396/2007/05
Shelf life:
2 years

Pharmaceutical forms available for follitropin alfa + lutropin alfa

Strengths available for follitropin alfa + lutropin alfa

  • (300UI+150UI)/0.48ml
  • (450UI+225UI)/0.72ml
  • (900UI+450UI)/1.44ml
  • 150UI/75UI

Official documents

The SmPC text is not displayed because a match to this medicine, strength and pharmaceutical form has not been confirmed.

The correspondence between the document and the displayed text is unconfirmed.

Source institution
EMA
Document language
English
Source record: first published
31/07/2009
Source record: last updated
18/06/2025