Leaflet LYXIT 12.5mg film-coated tablets


Indicated for: depression

Substance: tianeptine (antidepressant)

ATC: N06AX14 (Nervous system | Antidepressants | Other antidepressants)

Tianeptine is a medication primarily used for the treatment of major depressive disorder, but it also has benefits in managing anxiety and post-traumatic stress disorder (PTSD). It is an atypical antidepressant that works differently from other classes of antidepressants by modulating glutamate activity and increasing serotonin reuptake in the brain, without directly affecting serotonin receptors.

Tianeptine also has neuroprotective properties and can enhance neuroplasticity, which helps reduce depressive symptoms and improve cognitive function. It is taken orally, usually 2-3 times per day, as prescribed by a doctor.

Common side effects include nausea, drowsiness, dizziness, dry mouth, and constipation. In rare cases, it may cause dependence, especially at high doses or with misuse. For this reason, tianeptine use should be carefully monitored, and it is contraindicated in patients with a history of substance abuse.

General data about LYXIT 12.5mg

  • Substance: tianeptine
  • Date of last drug list: 01-05-2026
  • Commercial code: W57667005
  • Concentration: 12.5mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 90
  • Product type: generic
  • Price: 49.19 RON
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: ZAKLADY FARMACEUTYCZNE UNIA SPOLDZIELNIA PRACY - POLONIA
  • Holder: ARENA GROUP S.A. - ROMANIA
  • Number: 3446/2011/05
  • Shelf life: 3 years

Pharmaceutical forms available for tianeptine

Compensation lists for LYXIT 12.5mg Arena

B - Sublist B with 50% discount from the reference price

Price

Copayment

Patient

49.19 RON

24.59 RON

24.60 RON

G15 (C1) - Mental disorders

Price

Copayment

Patient

49.19 RON

49.19 RON

0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

49.19 RON

49.19 RON

0.00 RON