Avoid live vaccines
Avoid live vaccines during treatment if contraindicated.
Medicine information LEFLUNOMIDE ARENA 20mg film-coated tablets
- Product code:
- W62664003
- Quantity:
- 30
- Indicated for:
- rheumatoid arthritis
- Route of administration:
- oral
- Substance:
- leflunomide (immunomodulator)
- ATC
- L04AA13 — Antineoplastic and immunomodulating agents | Immunosuppressants | Immunosuppressants | Selective immunosuppressants
Leflunomide is a medication used for the treatment of rheumatoid arthritis and psoriatic arthritis. It works by inhibiting pyrimidine synthesis, thereby reducing inflammation and autoimmune responses.
The medication is taken orally, usually once daily, and the dose is adjusted based on the patient's response. Monitoring of liver and hematologic function is important during treatment.
Side effects may include nausea, diarrhea, hair loss, or elevated liver enzymes. In rare cases, severe reactions such as hepatotoxicity or pancytopenia may occur.
Leflunomide is not recommended for pregnant women or those planning to become pregnant, as well as patients with severe liver impairment or hypersensitivity to this medication.
The medication is taken orally, usually once daily, and the dose is adjusted based on the patient's response. Monitoring of liver and hematologic function is important during treatment.
Side effects may include nausea, diarrhea, hair loss, or elevated liver enzymes. In rare cases, severe reactions such as hepatotoxicity or pancytopenia may occur.
Leflunomide is not recommended for pregnant women or those planning to become pregnant, as well as patients with severe liver impairment or hypersensitivity to this medication.
General data about LEFLUNOMIDE ARENA 20mg
- Substance:
- leflunomide
- Date of latest medicines list:
- 01-10-2026
- Product code:
- W62664003
- Strength:
- 20mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 30
- Product type:
- Generic medicine
- Price:
- 124.07 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Strengths available for leflunomide
- 100mg
- 10mg
- 20mg
Official documents
Professional information (SmPC) - Romanian
Patient leaflet - Romanian
Packaging and labelling information - Romanian
The correspondence between the document and the displayed text is unconfirmed.
- Source institution
- ANMDMR
- Document language
- Romanian
Warnings:
Hepatotoxicity
This medicine may affect the liver.
Immunosuppression / infection risk
This medicine may increase the risk of infections.
Reimbursement lists for LEFLUNOMIDE ARENA 20mg Arena
G18 (C1) - Rheumatoid arthritis, psoriatic arthropathy, severe chronic psoriasis and juvenile arthritis
- Price
- 124.07 RON
- Copayment
- 104.50 RON
- Patient payment
- 19.57 RON
GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)
- Price
- 124.07 RON
- Copayment
- 104.50 RON
- Patient payment
- 19.57 RON