Indicated for: rheumatoid arthritis
Substance: leflunomide (immunomodulator)
ATC: L04AA13 (Antineoplastic and immunomodulating agents | Immunosuppressants | Selective immunosuppressants)
Leflunomide is a medication used for the treatment of rheumatoid arthritis and psoriatic arthritis. It works by inhibiting pyrimidine synthesis, thereby reducing inflammation and autoimmune responses.
The medication is taken orally, usually once daily, and the dose is adjusted based on the patient's response. Monitoring of liver and hematologic function is important during treatment.
Side effects may include nausea, diarrhea, hair loss, or elevated liver enzymes. In rare cases, severe reactions such as hepatotoxicity or pancytopenia may occur.
Leflunomide is not recommended for pregnant women or those planning to become pregnant, as well as patients with severe liver impairment or hypersensitivity to this medication.