LEDAGA 160mcg/G gel medication leaflet

L01AA05 • chlormethine • Antineoplastic and immunomodulating agents | Alkylating agents | Nitrogen mustard analogues

Chlormethine is a cytotoxic medicine used mainly as a skin gel for mycosis fungoides-type cutaneous T-cell lymphoma. It is not an ordinary anti-rash cream, but a local anticancer treatment that acts on abnormal cells in skin lesions and may help control patches, plaques or other affected areas.

The gel is usually applied once daily, only to the areas prescribed by the specialist. The skin should be completely dry before and after use. Wash your hands after application unless the hands are being treated. Avoid the eyes, mouth, mucous membranes, genitals and open wounds; anyone helping may need disposable gloves.

Side effects are commonly local: redness, itching, burning, pain, dryness, rash, dermatitis, blisters, ulcers, skin infection or darker skin colour in treated areas. Tell your doctor promptly if irritation is severe, the skin breaks down, there is discharge, fever, swelling, rapid worsening of lesions or signs of allergy.

Chlormethine requires careful handling and regular dermatology follow-up. Do not use more gel or apply it more often than prescribed. Ask for advice if you are pregnant, planning pregnancy or breastfeeding. Follow storage and disposal instructions, avoid accidental contact with other people and do not combine it with other skin products on the same area unless approved.