BEYONTTRA 356mg film-coated tablets medication leaflet

C01EB25 • acoramidis • Cardiovascular system | Other cardiac preparations

Acoramidis is a medicine used in adults with cardiomyopathy caused by transthyretin amyloidosis, either hereditary or wild-type. In this condition, transthyretin protein becomes unstable, forms amyloid deposits in the heart, and can lead to tiredness, shortness of breath, swollen legs, dizziness, or repeated hospital admissions for heart failure.

Acoramidis works by stabilising transthyretin, helping the protein remain bound together and reducing its tendency to form deposits. It does not remove existing amyloid immediately and it is not a cure, but it may slow worsening of heart damage and reduce the risk of cardiovascular death or heart-related hospitalisation.

The medicine is taken by mouth, usually twice daily, exactly as prescribed by the doctor. Tablets should be swallowed whole and may be taken with or without food. Do not stop treatment without medical advice. Regular follow-up is important so the care team can monitor symptoms, heart function, tolerability, and the other medicines used for heart failure or rhythm problems.

Common side effects include diarrhoea and gout, which is linked to high uric acid and may cause painful joint inflammation. Tell your doctor promptly if diarrhoea persists, joint pain is severe, breathing becomes worse, swelling increases, fainting occurs, or signs of allergy appear. Treatment should always be adapted to the individual patient’s condition.