Results for the substance solriamfetol

Solriamfetol is a medicine used in adults to improve wakefulness and reduce excessive daytime sleepiness in narcolepsy or obstructive sleep apnoea when primary treatment for apnoea, such as CPAP, has not adequately controlled sleepiness. It acts on dopamine and norepinephrine pathways, brain chemicals involved in alertness, but does not cure the underlying sleep disorder.

It is taken by mouth, usually in the morning on waking, at the dose prescribed by your doctor. It does not treat airway obstruction in sleep apnoea, so CPAP or other prescribed primary therapy should be continued. Avoid taking it late in the day because it can cause insomnia. The dose may be increased gradually.

Common side effects include headache, nausea, reduced appetite, anxiety, insomnia, irritability, dry mouth and palpitations. Solriamfetol can increase blood pressure and heart rate, which matters especially if you have cardiovascular disease. Contact your doctor if you develop chest pain, irregular heartbeat, severe agitation, mood changes, worsening anxiety or symptoms that interfere with daily life.

Blood pressure and heart rate should be checked before and during treatment. Tell your doctor if you have high blood pressure, heart attack, stroke, bipolar disorder, psychosis, significant anxiety or a history of stimulant misuse. Solriamfetol must not be used with monoamine oxidase inhibitors or within 14 days after stopping them.