Leaflet ZIFEX DUO 500mg / 200mg ovules
Indicated for: bacterial infections
Route of administration: vaginal
Substance: metronidazole + clotrimazole (nitroimidazole antimicrobial + azole antifungal)
ATC: G01AF20 (Genito urinary system and sex hormones | Antiinfectives and antiseptics, excl. combinations with corticosteroids | Imidazole derivatives)
Dose adjustment may be needed in liver disease.
Dose adjustment may be needed in kidney disease.
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Seek medical advice if severe or persistent diarrhea occurs.
This medicine may have important interactions with other medicines.
Use during pregnancy only on medical advice.
This medicine may increase the risk of heart rhythm disturbances.
Metronidazole and clotrimazole are used together in the treatment of mixed vaginal infections caused by bacteria and fungi. This combination is effective against bacterial vaginosis and vulvovaginal candidiasis.
Metronidazole is an antibacterial agent that targets anaerobic bacteria, while clotrimazole is an antifungal that combats fungal infections. Together, they provide broad-spectrum treatment for vaginal infections.
The medication is available as vaginal suppositories or creams and should be used as directed by a doctor. It is important to complete the full course of treatment to prevent recurrence of the infection.
Side effects may include local irritation or allergic reactions. Pregnant or breastfeeding women should consult a doctor before using this medication.
General data about ZIFEX DUO 500mg / 200mg
- Substance: metronidazole + clotrimazole
- Date of latest medicines list: 01-06-2026
- Product code: W61909003
- Concentration: 500mg / 200mg
- Pharmaceutical form: ovules
- Quantity: 14
- Product type: Generic medicine
- Price: 45.83 RON
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for metronidazole + clotrimazole
Concentrations available for metronidazole + clotrimazole
- 200mg/g+40mg/g
- 500mg/100mg
- 500mg/200mg
Compensation lists for ZIFEX DUO 500mg / 200mg Antibiotice
B - Sublist B with 50% discount from the reference price
Price
Copayment
Patient
45.83 RON
22.91 RON
22.92 RON