Fertility warning
This medicine may affect fertility.
Medicine information ZEJULA 100mg film-coated tablets
Niraparib is a PARP (poly-ADP-ribose polymerase) enzyme inhibitor primarily used for the treatment of recurrent ovarian cancer. This medication is indicated for patients who have responded to platinum-based chemotherapy, serving as a maintenance therapy. Niraparib works by inhibiting DNA repair in cancer cells, leading to their death.
This drug is usually administered orally, once daily, with the dose adjusted based on the patient's weight and individual tolerance. Common side effects include nausea, fatigue, anemia, and constipation. Regular monitoring is essential to assess potential adverse reactions.
Niraparib is contraindicated in patients with hypersensitivity to the active substance or any of its excipients. Additionally, its use during pregnancy and breastfeeding is not recommended, as it may harm the fetus or infant.
This medication represents an important option for patients with ovarian cancer, offering a chance to prolong survival without disease progression. It is crucial that treatment is administered under the supervision of a specialist physician.
This drug is usually administered orally, once daily, with the dose adjusted based on the patient's weight and individual tolerance. Common side effects include nausea, fatigue, anemia, and constipation. Regular monitoring is essential to assess potential adverse reactions.
Niraparib is contraindicated in patients with hypersensitivity to the active substance or any of its excipients. Additionally, its use during pregnancy and breastfeeding is not recommended, as it may harm the fetus or infant.
This medication represents an important option for patients with ovarian cancer, offering a chance to prolong survival without disease progression. It is crucial that treatment is administered under the supervision of a specialist physician.
General data about ZEJULA 100mg
- Substance:
- niraparib
- Date of latest medicines list:
- 01-10-2026
- Product code:
- W71587006
- Strength:
- 100mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 56
- Product type:
- Original
- Price:
- 17884.37 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Combinations with other substances
Official documents
The SmPC text is not displayed because a match to this medicine, strength and pharmaceutical form has not been confirmed.
- Added to database:
- 27/11/2017
- Source record updated:
- 10/06/2026
Warnings:
Cytotoxic / special handling
Handle with special care.
Contraception required
Effective contraception is required during treatment.
Contraindicated during breastfeeding
Do not use this medicine while breastfeeding.
Contraindicated during pregnancy
Do not use this medicine during pregnancy.
Hepatotoxicity
This medicine may affect the liver.
Major drug interactions
This medicine may have important interactions with other medicines.
Myelosuppression / agranulocytosis
This medicine may lower blood cell counts.
Additional monitoring
This medicine is subject to additional monitoring.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Severe skin reactions
Stop taking the medicine and seek urgent medical help if a severe rash occurs.