Leaflet VIRICIN 250mg powder for solution for infusion

Indicated for: herpes virus infections

Route of administration: infusion

Substance: acyclovir (antiviral)

ATC: J05AB01 (Antiinfectives for systemic use | Direct acting antivirals | Nucleosides and nucleotides excl. reverse transcriptase inhibitors)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Acyclovir is an antiviral medication used to treat infections caused by herpes viruses, such as herpes simplex (HSV) and varicella-zoster (VZV). It is indicated for the treatment of oral and genital herpes, chickenpox, and shingles, as well as for preventing recurrences in patients with recurrent herpes infections.

Acyclovir works by inhibiting viral DNA replication, thereby reducing the severity and duration of symptoms. It can be administered orally, topically (as a cream), or intravenously, depending on the severity of the infection.

Common side effects include nausea, diarrhea, headaches, or local irritation (with topical use). In rare cases, intravenous administration may cause kidney damage or severe allergic reactions. It is important for patients to stay well-hydrated during treatment to reduce the risk of kidney toxicity.

Acyclovir is effective in managing herpes infections but does not cure the infection, as the virus remains dormant in the body. Treatment should be started as early as possible after symptom onset to maximize effectiveness.

General data about VIRICIN 250mg

  • Substance: acyclovir
  • Date of latest medicines list: 01-06-2026
  • Product code: W67998002
  • Concentration: 250mg
  • Pharmaceutical form: powder for solution for infusion
  • Quantity: 5
  • Product type: Generic medicine
  • Price: 258.54 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: SOFARIMEX - INDUSTRIA QUIMICA E FARMACEUTICA S.A. - PORTUGALIA
  • Holder: MEDOCHEMIE LTD. - CIPRU
  • Number: 13826/2021/02
  • Shelf life: 4 years; after reconstitution it is used immediately

Concentrations available for acyclovir

  • 200mg
  • 250mg
  • 25mg/ml
  • 3%
  • 30mg/g
  • 400mg
  • 5%
  • 500mg
  • 50mg
  • 50mg/g

Combinations with other substances

Compensation lists for VIRICIN 250mg Medochemie

A - Sublist A with 90% discount from the reference price

Price

Copayment

Patient

258.54 RON

208.16 RON

50.38 RON

NHP 1.A (C2) - People with HIV/AIDS and post-exposure treatment

Price

Copayment

Patient

258.54 RON

179.42 RON

79.12 RON

NHP 9.1 (C2) - Spinal cord transplant

Price

Copayment

Patient

258.54 RON

179.42 RON

79.12 RON

NHP 9.4 (C2) - Kidney transplant, combined kidney and pancreas transplant

Price

Copayment

Patient

258.54 RON

179.42 RON

79.12 RON

NHP 9.6 (C2) - Lung transplant

Price

Copayment

Patient

258.54 RON

179.42 RON

79.12 RON

NHP 9.7 (C2) - Outpatient treatment of transplant patients

Price

Copayment

Patient

258.54 RON

179.42 RON

79.12 RON