Avoid grapefruit
Avoid grapefruit and grapefruit juice.
Leaflet VASILIP 40mg film-coated tablets
- Product code:
- W13137001
- Quantity:
- 28
- Indicated for:
- dyslipidemia
- Route of administration:
- oral
- Substance:
- simvastatin (statin lipid-lowering agent)
- ATC
- C10AA01 — Cardiovascular system | Lipid modifying agents | Lipid modifying agents, plain | Hmg coa reductase inhibitors
Precautions:
Hepatotoxicity
This medicine may affect the liver.
Major drug interactions
This medicine may have important interactions with other medicines.
Myopathy / rhabdomyolysis
Seek medical advice if unexplained muscle pain occurs.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Pregnancy warning
Use during pregnancy only on medical advice.
Simvastatin is a medication used to lower cholesterol and triglyceride levels in the blood, and it is indicated for the prevention of cardiovascular diseases such as heart attack and stroke. It belongs to the class of statins, which work by inhibiting the enzyme HMG-CoA reductase, responsible for cholesterol production in the liver.
Simvastatin is taken orally, usually once daily in the evening, as cholesterol synthesis is more active at night. It is used in combination with a healthy diet, exercise, and other cholesterol-lowering measures.
Common side effects include headaches, nausea, constipation, mild muscle pain, and fatigue. In rare cases, it may cause more serious reactions, such as rhabdomyolysis (a severe condition involving muscle tissue breakdown), liver dysfunction, or elevated liver enzyme levels.
Simvastatin is contraindicated in individuals with active liver disease, pregnant or breastfeeding women, and those taking certain medications that may interact with it (such as some antifungals or antibiotics). It is important for patients to follow their doctor's recommendations and undergo regular blood tests to monitor liver function and cholesterol levels.
Simvastatin is taken orally, usually once daily in the evening, as cholesterol synthesis is more active at night. It is used in combination with a healthy diet, exercise, and other cholesterol-lowering measures.
Common side effects include headaches, nausea, constipation, mild muscle pain, and fatigue. In rare cases, it may cause more serious reactions, such as rhabdomyolysis (a severe condition involving muscle tissue breakdown), liver dysfunction, or elevated liver enzyme levels.
Simvastatin is contraindicated in individuals with active liver disease, pregnant or breastfeeding women, and those taking certain medications that may interact with it (such as some antifungals or antibiotics). It is important for patients to follow their doctor's recommendations and undergo regular blood tests to monitor liver function and cholesterol levels.
General data about VASILIP 40mg
- Substance:
- simvastatin
- Date of latest medicines list:
- 01-03-2022
- Product code:
- W13137001
- Concentration:
- 40mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 28
- Product type:
- Generic medicine
- Prescription status:
- P-6L — Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.
Concentrations available for simvastatin
- 10mg
- 20mg
- 30mg
- 40mg
- 5mg
- 80mg