Leaflet VANTAS 50mg implant


Indicated for: central precocious puberty; prostate cancer

Route of administration: implantation

Substance: histreline (antineoplastic agent)

ATC: H01CA03 (Systemic hormonal preparations, excluding sex hormones and insulins | Hypothalamic hormones | Gonadotropin-releasing hormones)

Precautions:
Fertility warning
Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment
Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling
Cytotoxic / special handling

Handle with special care.

Contraception required
Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding
Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis
Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Histrelin is a gonadotropin-releasing hormone (GnRH) agonist used for the treatment of advanced prostate cancer and precocious puberty. It works by reducing the production of testosterone or estrogen, thereby suppressing the growth of hormone-sensitive tumors.

The medication is administered as a subcutaneous implant, as directed by a doctor. The implant gradually releases the drug over several months.

Side effects may include hot flashes, headache, decreased libido, or reactions at the implantation site. In rare cases, severe allergic reactions may occur.

Histrelin is not recommended for patients with hypersensitivity to this medication or pregnant women.

General data about VANTAS 50mg

  • Substance: histreline
  • Date of last drug list: 01-04-2014
  • Commercial code: W58114001
  • Concentration: 50mg
  • Pharmaceutical form: implant
  • Quantity: 1
  • Product type: original
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).