Leaflet TOPOTECAN EBEWE 1mg / ml concentrate for solution for infusion
Indicated for: ovarian cancer; small cell lung cancer
Route of administration: infusion
Substance: topotecan (topoisomerase inhibitor)
ATC: L01XX17 (Antineoplastic and immunomodulating agents | Other antineoplastic agents)
This medicine may affect fertility.
Handle with special care.
Effective contraception is required during treatment.
Do not use this medicine while breastfeeding.
Do not use this medicine during pregnancy.
This medicine may affect the liver.
This medicine may have important interactions with other medicines.
This medicine may lower blood cell counts.
This medicine is subject to additional monitoring.
Periodic laboratory tests may be required during treatment.
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Topotecan is an antineoplastic agent from the class of topoisomerase I inhibitors, used in the treatment of recurrent ovarian cancer, small cell lung cancer, and other types of cancer. It works by inhibiting the enzyme topoisomerase I, which is essential for DNA replication, thereby causing tumor cell death.
Topotecan is administered intravenously or orally, usually in treatment cycles, with the dose adjusted based on the patient's body weight and tolerability. It is often used in combination with other chemotherapeutic agents to enhance treatment efficacy.
Common side effects include neutropenia, anemia, nausea, vomiting, diarrhea, and fatigue. In rare cases, severe adverse reactions such as serious infections or pulmonary toxicity may occur. Careful monitoring of hematological parameters and the patient's overall condition is essential during treatment.
Topotecan is an important therapeutic option for patients with advanced cancer, contributing to disease control and prolonged survival.
General data about TOPOTECAN EBEWE 1mg / ml
- Substance: topotecan
- Date of latest medicines list: 01-06-2018
- Product code: W56261007
- Concentration: 1mg / ml
- Pharmaceutical form: concentrate for solution for infusion
- Quantity: 1
- Product type: Generic medicine
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for topotecan
Concentrations available for topotecan
- 0.25mg
- 1mg
- 1mg/1ml
- 1mg/ml
- 4mg
- 4mg/4ml
- 500mg