Active substance

Results for the substance mitotane

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About this active substance

Mitotane is a cytostatic agent used for the treatment of advanced adrenocortical carcinoma. It works by inhibiting adrenal cortex function and destroying tumor cells, reducing the production of steroid hormones.

The medication is taken orally, usually in divided doses, with the dose adjusted based on the patient's response and plasma levels of the drug. Common side effects include nausea, vomiting, diarrhea, and fatigue.

Mitotane is contraindicated in patients with hypersensitivity to the active substance. Its use also requires careful monitoring of liver function and hormone levels.

This medication is an important option for patients with adrenocortical carcinoma, helping to slow disease progression and alleviate symptoms.