Fertility warning
This medicine may affect fertility.
Leaflet SIKLOS 1000mg film-coated tablets
- Product code:
- W52768001
- Quantity:
- 30
- Indicated for:
- myeloproliferative neoplasms; sickle cell disease
- Route of administration:
- oral
- Substance:
- hydroxycarbamide (antineoplastic agent)
- ATC
- L01XX05 — Antineoplastic and immunomodulating agents | Other antineoplastic agents
Precautions:
Dose adjustment in hepatic impairment
Dose adjustment may be needed in liver disease.
Cytotoxic / special handling
Handle with special care.
Contraception required
Effective contraception is required during treatment.
Contraindicated during breastfeeding
Do not use this medicine while breastfeeding.
Contraindicated during pregnancy
Do not use this medicine during pregnancy.
Hepatotoxicity
This medicine may affect the liver.
Major drug interactions
This medicine may have important interactions with other medicines.
Myelosuppression / agranulocytosis
This medicine may lower blood cell counts.
Additional monitoring
This medicine is subject to additional monitoring.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Severe skin reactions
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Hydroxyurea is a medication used to treat certain types of cancer, such as chronic myeloid leukemia, and other conditions like sickle cell anemia. It works by inhibiting DNA synthesis, which slows the growth of cancerous or abnormal cells.
The medication is taken orally, as directed by a doctor.
Side effects may include nausea, vomiting, decreased blood cell counts, fatigue, or skin rashes. In rare cases, severe allergic reactions or hematologic toxicity may occur.
Patients should be closely monitored during treatment and inform their doctor about any other medications they are taking. Pregnant or breastfeeding women should not use this medication.
The medication is taken orally, as directed by a doctor.
Side effects may include nausea, vomiting, decreased blood cell counts, fatigue, or skin rashes. In rare cases, severe allergic reactions or hematologic toxicity may occur.
Patients should be closely monitored during treatment and inform their doctor about any other medications they are taking. Pregnant or breastfeeding women should not use this medication.
General data about SIKLOS 1000mg
- Substance:
- hydroxycarbamide
- Date of latest medicines list:
- 01-07-2013
- Product code:
- W52768001
- Concentration:
- 1000mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 30
- Product type:
- Original
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for hydroxycarbamide
Concentrations available for hydroxycarbamide
- 1000mg
- 500mg