ROBINUL-NEOSTIGMINE 0.5mg / ml 2.5mg / ml injectible solution medication leaflet

A03AB02 • glycopyrronium bromide + neostigmine methylsulfate • Alimentary tract and metabolism | Drugs for functional gastrointestinal disorders | Synthetic anticholinergics, quaternary ammonium compounds

Glycopyrronium bromide + neostigmine methylsulfate is a combination of medications used to reverse the effects of muscle relaxants administered during surgery. It helps restore normal muscle function after general anesthesia.

Glycopyrronium bromide is an anticholinergic agent that reduces side effects such as excessive secretions or bradycardia (slowed heart rate) caused by neostigmine. Neostigmine methylsulfate is a cholinesterase inhibitor that increases acetylcholine levels, aiding in the restoration of muscle contraction.

This combination is effective and well-tolerated but may cause side effects such as dry mouth, nausea, dizziness, or changes in heart rate. It is important for the medication to be administered under strict medical supervision, usually in a hospital setting.