Indicated for: vasodilatory shock; diabetes insipidus
Route of administration: infusion
Substance: vasopressin (argipressin) (antidiabetic)
ATC: H01BA01 (Systemic hormonal preparations, excluding sex hormones and insulins | Posterior pituitary lobe hormones | Vasopressin and analogues)
Vasopressin, also known as argipressin, is an antidiuretic hormone used in medicine for the treatment of conditions such as septic shock, gastrointestinal bleeding, and central diabetes insipidus. It acts by stimulating V1 and V2 receptors, leading to vasoconstriction and increased water reabsorption in the kidneys. Through these mechanisms, vasopressin helps maintain blood pressure and fluid balance.
Vasopressin is administered intravenously or intramuscularly, depending on the therapeutic indication, and the dosage is adjusted based on the patient's response. Treatment requires careful monitoring to prevent complications such as hyponatremia or tissue ischemia.
Common side effects include nausea, abdominal pain, headache, and hypertension. In rare cases, severe adverse reactions such as cardiac arrhythmias or myocardial ischemia may occur.
Vasopressin (argipressin) is an essential medication in the management of critical conditions, helping to stabilize patients and improve their prognosis.