Leaflet REFEN 75mg 25mg / ml solution for injection / infusion


Indicated for: pain and inflammation

Route of administration: injectable / infusion

Substance: diclofenac (nonsteroidal anti-inflammatory drug)

ATC: M01AB05 (Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Acetic acid derivatives and related substances)

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with various conditions. It is effective for managing muscle pain, joint pain, back pain, arthritis, ankylosing spondylitis, menstrual pain, and other inflammatory conditions.

It works by inhibiting the synthesis of prostaglandins, substances involved in inflammation and pain, thereby reducing inflammation, fever, and pain. Diclofenac is available in the form of tablets, capsules, gels, patches, suppositories, and injectable solutions.

Side effects may include nausea, vomiting, abdominal pain, heartburn, diarrhea, dizziness, or, rarely, allergic reactions. Long-term use or high doses may increase the risk of gastric ulcers, gastrointestinal bleeding, kidney damage, or cardiovascular events.

Diclofenac is contraindicated in patients with NSAID allergies, active gastric ulcers, severe renal failure, liver failure, or severe heart failure. It is important to use it as directed by a healthcare provider.

General data about REFEN 75mg 25mg / ml

  • Substance: diclofenac
  • Date of last drug list: 01-05-2026
  • Commercial code: W55024001
  • Concentration: 25mg / ml
  • Pharmaceutical form: solution for injection / infusion
  • Packing volume: 3 ml
  • Product type: generic
  • Price: 21.25 RON
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: STADA M&D S.R.L. - ROMANIA
  • Holder: STADA HEMOFARM S.R.L. - ROMANIA
  • Number: 1958/2009/01
  • Shelf life: 3 years

Concentrations available for diclofenac

  • 0.074g/100ml
  • 0.1%
  • 1%
  • 100mg
  • 10mg/g
  • 11.6mg
  • 11.6mg/g
  • 12.5mg
  • 120mg
  • 140mg
  • 150mg
  • 1mg/ml
  • 23.2mg/g
  • 25mg
  • 25mg/ml
  • 30mg/g
  • 30mg/ml
  • 37.5mg/ml
  • 5%
  • 50mg
  • 50mg/g
  • 60mg
  • 75mg
  • 75mg/3ml

Compensation lists for REFEN 75mg 25mg / ml STADA

A - Sublist A with 90% discount from the reference price

Price

Copayment

Patient

21.25 RON

11.32 RON

9.93 RON

G18 (C1) - Rheumatoid arthritis, psoriatic arthropathy, severe chronic psoriasis and juvenile arthritis

Price

Copayment

Patient

21.25 RON

19.49 RON

1.76 RON

G19 (C1) - Ankylosing spondylitis

Price

Copayment

Patient

21.25 RON

19.49 RON

1.76 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

21.25 RON

19.49 RON

1.76 RON