Leaflet PROTAMINSULFAT LEO PHARMA 1400 ANTI-HEPARINUI/ml 10mg / ml solution for injection / infusion


Indicated for: constipation

Route of administration: injectable / infusion

Substance: protamine sulfate (antidote)

ATC: V03AB14 (Various | All other therapeutic products | Antidotes)

Protamine sulfate is used to neutralize the anticoagulant effects of heparin, particularly during surgical procedures or in cases of heparin overdose. It works by forming a stable complex with heparin, inhibiting its activity.

The medication is administered intravenously, as directed by a doctor, usually as a slow injection. It is important for patients to be monitored for adverse reactions during administration.

Patients should be aware of potential side effects, such as allergic reactions, hypotension, or bradycardia. It is important to inform the doctor of any unusual symptoms.

Common side effects include allergic reactions, hypotension, and bradycardia. In rare cases, severe reactions such as anaphylactic shock may occur. Patients should be informed of these risks before use.

General data about PROTAMINSULFAT LEO PHARMA 1400 ANTI-HEPARINUI/ml 10mg / ml

  • Substance: protamine sulfate
  • Date of last drug list: 01-10-2025
  • Commercial code: W69119001
  • Concentration: 10mg / ml
  • Pharmaceutical form: solution for injection / infusion
  • Quantity: 5
  • Product type: generic
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: CENEXI SAS - FRANTA
  • Holder: ALLIANCE HEALTHCARE ROMANIA S.R.L. - ROMANIA
  • Number: 745/2022/01
  • Shelf life: 3 years

Pharmaceutical forms available for protamine sulfate

Concentrations available for protamine sulfate

  • 10mg/ml
  • 1400Ui/ml