PAMIDRONATE HOSPIRA 3mg / ml concentrate for solution for infusion medication leaflet

M05BA03 • pamidronic acid • Musculo-skeletal system | Drugs affecting bone structure and mineralization | Bisphosphonates

Pamidronic acid is a bisphosphonate used to treat hypercalcemia associated with cancer and to prevent skeletal complications in patients with bone metastases. It works by inhibiting osteoclast-mediated bone resorption, thereby reducing bone loss.

It is administered intravenously and is effective in lowering high calcium levels in the blood, which can occur in certain types of cancer. It is also used to reduce the risk of bone fractures and other complications in patients with bone metastases.

Common side effects include fever, flu-like symptoms, and bone or muscle pain. In rare cases, it may cause osteonecrosis of the jaw, especially in patients who have recently undergone dental procedures.

Patients receiving pamidronic acid treatment should be monitored for kidney function, as the drug can affect the kidneys, particularly at high doses.