NOPREX 35mcg / h transdermal patch medication leaflet

N02AE01 • buprenorphine • Nervous system | Opioids | Oripavine derivatives

Buprenorphinum is an opioid analgesic used for the treatment of moderate to severe pain and for managing opioid dependence. It is a partial agonist of mu-opioid receptors and an antagonist of kappa-opioid receptors, providing strong analgesic effects with a lower risk of respiratory depression compared to other opioids.

The medication is available in the form of sublingual tablets, transdermal patches, or injections, and the dosage is adjusted based on the severity of pain or the patient's needs in opioid dependence treatment.

Common side effects include nausea, constipation, dizziness, drowsiness, and excessive sweating. In rare cases, more severe adverse effects such as severe respiratory depression or allergic reactions may occur.

Buprenorphinum is not recommended for pregnant or breastfeeding women unless the benefits outweigh the risks. Patients should inform their doctor about all medications they are taking to avoid drug interactions. Additionally, the use of this medication requires careful medical supervision to prevent abuse, dependence, or other complications associated with opioids.