Medication leaflets

Active substance

Results for the substance buprenorphine naloxone

4 results

About this active substance

The combination of buprenorphine and nalaxone is used for the treatment of opioid dependence as part of a comprehensive therapy program that includes counseling and psychosocial support. Buprenorphine is a partial agonist of mu-opioid receptors, helping to reduce withdrawal symptoms and control opioid cravings, while nalaxone is an opioid receptor antagonist designed to prevent abuse by injection.

The medication is administered as sublingual tablets or buccal films, as directed by a doctor. The dosage is adjusted based on the individual needs of the patient and their response to treatment.

Common side effects include nausea, constipation, insomnia, excessive sweating, and headaches. In rare cases, more severe adverse effects such as severe respiratory depression or allergic reactions may occur.

This combination is not recommended for pregnant or breastfeeding women unless the benefits outweigh the risks. Patients should inform their doctor about all medications they are taking to avoid drug interactions. Additionally, the use of this medication requires careful medical supervision to prevent abuse, dependence, or other complications associated with opioids.