Leaflet NO-SPA 40mg / 2ml solution for injection

Indicated for: gastrointestinal spasms; functional abdominal pain

Route of administration: injectable

Substance: drotaverine (gastrointestinal antispasmodic)

ATC: A03AD02 (Alimentary tract and metabolism | Drugs for functional gastrointestinal disorders | Papaverine and derivatives)

Drotaverine is an antispasmodic medication used to relieve pain and spasms of smooth muscles in various parts of the body. It is commonly prescribed for conditions such as biliary colic, renal colic, menstrual pain, or other types of abdominal pain caused by spasms.

This medication works by inhibiting the enzyme phosphodiesterase-4 (PDE-4), which leads to the relaxation of smooth muscles in the gastrointestinal tract, urinary system, bile ducts, and blood vessels. Through this mechanism, drotaverine helps alleviate pain and improve blood flow in the affected areas.

Drotaverine is administered in the form of tablets or injectable solutions, depending on the severity of the symptoms. The usual adult dose is 40-80 mg, 2-3 times a day, but this may vary based on the doctor’s recommendations and the patient’s condition.

Side effects of drotaverine are rare and usually mild. These may include nausea, dizziness, headache, palpitations, or allergic reactions. In very rare cases, more severe adverse effects, such as low blood pressure or breathing difficulties, may occur and require immediate medical attention.

Drotaverine is not recommended for patients with severe liver, kidney, or heart failure, as well as those allergic to the active substance. It is important to use the medication as directed by a doctor, and patients should avoid overdosing to prevent adverse effects.