Leaflet NEFRIX 25mg tablets

Indicated for: hypertension; edema

Route of administration: oral

Substance: hydrochlorothiazide (diuretic)

ATC: C03AA03 (Cardiovascular system | Low-ceiling diuretics, thiazides | Thiazides, plain)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Photosensitivity
Photosensitivity

Avoid excessive exposure to sunlight or UV radiation.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Electrolyte disturbances
Electrolyte disturbances

This medicine may change blood electrolyte levels.

Hydrochlorothiazide is a thiazide diuretic used for the treatment of hypertension and edema associated with heart failure, kidney, or liver diseases. It works by increasing the excretion of sodium and water in the kidneys, reducing blood volume and blood pressure.

The medication is taken orally, as directed by a doctor, usually once daily in the morning. It is important for patients to follow the treatment regimen and undergo regular check-ups to monitor blood pressure and kidney function.

Patients should be aware of potential side effects, such as dizziness, electrolyte imbalances, or increased uric acid levels. It is important to inform the doctor of any unusual symptoms.

Common side effects include dizziness, electrolyte imbalances, and increased uric acid levels. In rare cases, severe reactions such as hyponatremia or allergic reactions may occur. Patients should be informed of these risks before starting treatment.

General data about NEFRIX 25mg

  • Substance: hydrochlorothiazide
  • Date of latest medicines list: 01-06-2026
  • Product code: W43198002
  • Concentration: 25mg
  • Pharmaceutical form: tablets
  • Quantity: 25
  • Product type: Generic medicine
  • Price: 36.67 RON
  • Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.

Marketing authorisation

  • Manufacturer: ZENTIVA S.A. - ROMANIA
  • Holder: ZENTIVA S.A. - ROMANIA
  • Number: 11406/2019/01
  • Shelf life: 2 years

Compensation lists for NEFRIX 25mg Zentiva

A - Sublist A with 90% discount from the reference price

Price

Copayment

Patient

36.67 RON

33.00 RON

3.67 RON

G1 (C1) - Chronic heart failure (NYHA class III or IV)

Price

Copayment

Patient

36.67 RON

36.67 RON

0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

36.67 RON

36.67 RON

0.00 RON