Medication leaflets

Active substance

Results for the substance aliskiren hydrochlorothiazide

4 results

About this active substance

Aliskiren in combination with hydrochlorothiazide is a treatment used for managing high blood pressure. Aliskiren is a direct renin inhibitor that reduces the production of angiotensin I and II, thereby lowering blood pressure. Hydrochlorothiazide is a thiazide diuretic that helps eliminate excess water and salt from the body, contributing to blood pressure reduction.

This combination is administered orally, usually once daily, as directed by a doctor. It is particularly indicated for patients who do not respond adequately to monotherapy or require stricter blood pressure control.

Side effects may include dizziness, headache, fatigue, increased potassium levels (hyperkalemia), or decreased sodium levels. In rare cases, severe reactions such as angioedema or kidney failure may occur.

Patients should be regularly monitored for kidney function, electrolyte levels, and blood pressure. It is important to strictly follow the doctor's recommendations and avoid the concurrent use of other medications that may affect the renin-angiotensin-aldosterone system. This combination is an effective option for patients with essential hypertension.