Fertility warning
This medicine may affect fertility.
Leaflet NAMAXIR 25mg solution for injection in pre-filled syringe
- Product code:
- W62239002
- Quantity:
- 4
- Indicated for:
- cancer; autoimmune inflammatory diseases
- Route of administration:
- injectable
- Substance:
- methotrexate (antimetabolite antineoplastic)
- ATC
- L04AX03 — Antineoplastic and immunomodulating agents | Immunosuppressants | Immunosuppressants | Other immunosuppressants
Precautions:
Dose adjustment in hepatic impairment
Dose adjustment may be needed in liver disease.
Cytotoxic / special handling
Handle with special care.
Contraception required
Effective contraception is required during treatment.
Contraindicated during breastfeeding
Do not use this medicine while breastfeeding.
Contraindicated during pregnancy
Do not use this medicine during pregnancy.
Avoid live vaccines
Avoid live vaccines during treatment if contraindicated.
Hepatotoxicity
This medicine may affect the liver.
Immunosuppression / infection risk
This medicine may increase the risk of infections.
Major drug interactions
This medicine may have important interactions with other medicines.
Myelosuppression / agranulocytosis
This medicine may lower blood cell counts.
Additional monitoring
This medicine is subject to additional monitoring.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Severe skin reactions
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Teratogenic / fetal risk
This medicine may affect fetal development.
Methotrexate is a medication used to treat various conditions, including autoimmune diseases and certain types of cancer. It is commonly prescribed for rheumatoid arthritis, severe psoriasis, psoriatic arthritis, and other chronic inflammatory diseases. It is also used in chemotherapy to treat leukemia, lymphomas, and other cancers.
Methotrexate works by inhibiting an enzyme called dihydrofolate reductase, which is essential for DNA synthesis and cell division. In autoimmune diseases, this mechanism helps reduce inflammation and immune system activity, while in cancer, it slows the growth of tumor cells.
Side effects may include nausea, vomiting, fatigue, mouth ulcers, hair loss, and a decrease in blood cell counts. In rare cases, more serious reactions can occur, such as liver damage, lung problems, or bone marrow suppression. It is crucial to take methotrexate as prescribed by a doctor, with regular blood tests to monitor for potential complications.
Methotrexate works by inhibiting an enzyme called dihydrofolate reductase, which is essential for DNA synthesis and cell division. In autoimmune diseases, this mechanism helps reduce inflammation and immune system activity, while in cancer, it slows the growth of tumor cells.
Side effects may include nausea, vomiting, fatigue, mouth ulcers, hair loss, and a decrease in blood cell counts. In rare cases, more serious reactions can occur, such as liver damage, lung problems, or bone marrow suppression. It is crucial to take methotrexate as prescribed by a doctor, with regular blood tests to monitor for potential complications.
General data about NAMAXIR 25mg
- Substance:
- methotrexate
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W62239002
- Concentration:
- 25mg
- Pharmaceutical form:
- solution for injection in pre-filled syringe
- Quantity:
- 4
- Product type:
- Generic medicine
- Price:
- 370.45 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for methotrexate
Concentrations available for methotrexate
- 100mg/ml
- 10mg
- 10mg/ml
- 12.5mg
- 12.5mg/ml
- 15mg
- 15mg/ml
- 17.5mg
- 17.5mg/ml
- 2.5mg
- 2.5mg/ml
- 20mg
- 20mg/ml
- 22.5mg
- 22.5mg/ml
- 25mg
- 25mg/ml
- 27.5mg
- 27.5mg/ml
- 2mg/ml
- 30mg
- 30mg/ml
- 50mg
- 50mg/ml
- 5mg
- 5mg/ml
- 7.5mg
- 7.5mg/ml
Compensation lists for NAMAXIR 25mg Actavis
G18 (C1) - Rheumatoid arthritis, psoriatic arthropathy, severe chronic psoriasis and juvenile arthritis
- Price
- 370.45 RON
- Copayment
- 370.45 RON
- Patient
- 0.00 RON