Active substance
Results for the substance diroximel fumarate
1 result
About this active substance
Diroximel fumarate is a medication used to treat relapsing-remitting multiple sclerosis (RRMS), an autoimmune disease that affects the central nervous system. It helps reduce the frequency of relapses and slows the progression of disability.
Diroximel fumarate is a prodrug that is converted in the body into monomethyl fumarate, an active compound that reduces inflammation and oxidative stress in the central nervous system. This mechanism protects neurons and myelin, the protective layer of nerve fibers, preventing damage caused by autoimmune attacks.
The medication is taken orally in capsule form and is well-tolerated by most patients. Common side effects include flushing (a sensation of warmth and redness), nausea, diarrhea, and abdominal pain. These side effects are usually mild and temporary.
In rare cases, diroximel fumarate may cause a decrease in lymphocyte count (lymphopenia), which can increase the risk of infections. There is also a very low risk of progressive multifocal leukoencephalopathy (PML), a serious viral brain infection. For this reason, patients need regular blood tests to monitor their health.
Patients should strictly follow their doctor’s instructions regarding dosage and inform the medical team about any side effects or other medications they are taking. It is important not to discontinue treatment without consulting a doctor, as this may worsen multiple sclerosis symptoms.
Diroximel fumarate is a prodrug that is converted in the body into monomethyl fumarate, an active compound that reduces inflammation and oxidative stress in the central nervous system. This mechanism protects neurons and myelin, the protective layer of nerve fibers, preventing damage caused by autoimmune attacks.
The medication is taken orally in capsule form and is well-tolerated by most patients. Common side effects include flushing (a sensation of warmth and redness), nausea, diarrhea, and abdominal pain. These side effects are usually mild and temporary.
In rare cases, diroximel fumarate may cause a decrease in lymphocyte count (lymphopenia), which can increase the risk of infections. There is also a very low risk of progressive multifocal leukoencephalopathy (PML), a serious viral brain infection. For this reason, patients need regular blood tests to monitor their health.
Patients should strictly follow their doctor’s instructions regarding dosage and inform the medical team about any side effects or other medications they are taking. It is important not to discontinue treatment without consulting a doctor, as this may worsen multiple sclerosis symptoms.