Leaflet METADON BIOEEL 20mg tablets


Indicated for: severe pain; opioid dependence

Route of administration: oral

Substance: methadone (opioid analgesic)

ATC: N07BC02 (Nervous system | Drugs used in addictive disorders | Drugs used in opioid dependence)

Precautions:
Driving impairment
Driving impairment

This medicine may affect your ability to drive or use machines.

Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Dependence / abuse
Dependence / abuse

This medicine may cause dependence or be misused.

Respiratory depression
Respiratory depression

May slow breathing, especially with alcohol or sedatives.

Avoid alcohol
Avoid alcohol

Avoid alcohol during treatment.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Elderly warning
Elderly warning

Older people may have an increased risk of side effects.

Cardiac risk / QT prolongation / arrhythmias
Cardiac risk / QT prolongation / arrhythmias

This medicine may increase the risk of heart rhythm disturbances.

Withdrawal / do not stop abruptly
Withdrawal / do not stop abruptly

Do not stop treatment abruptly without medical advice.

Drowsiness / sedation
Drowsiness / sedation

This medicine may cause drowsiness or reduced alertness.

Methadone is a synthetic opioid analgesic primarily used for the treatment of severe chronic pain and as part of substitution therapy for opioid dependence, such as heroin addiction. It is a long-acting medication that helps reduce withdrawal symptoms and cravings for opioids.

In pain management, methadone is effective for severe pain that does not respond to other analgesics. It is also used in substitution programs to stabilize opioid-dependent patients, reducing the risk of relapse and the use of illicit drugs. Methadone does not produce the intense euphoria associated with other opioids, making it more suitable for this purpose.

However, methadone use requires careful monitoring, as it can cause side effects such as respiratory depression, excessive sedation, or cardiac arrhythmias. It is essential for patients to adhere to the prescribed dosage and be supervised by a physician, especially during the initial weeks of treatment.

Methadone is a critical medication in managing opioid dependence and chronic pain, but its use should be part of a comprehensive treatment plan that includes counseling and psychological support. Patients should be informed about the risks and benefits of the treatment to ensure safe and effective use.

General data about METADON BIOEEL 20mg

  • Substance: methadone
  • Date of last drug list: 01-06-2026
  • Commercial code: W55532002
  • Concentration: 20mg
  • Pharmaceutical form: tablets
  • Quantity: 50
  • Product type: generic
  • Price: 110.10 RON
  • Prescription restrictions: TAB2 - Medicines that are issued with a special prescription (narcotics) in yellow color.

Marketing authorisation

  • Manufacturer: EXTRACTUMPHARMA CO. LT - UNGARIA
  • Holder: BIO EEL SRL - ROMANIA
  • Number: 8411/2015/02
  • Shelf life: 2 years

Pharmaceutical forms available for methadone

Concentrations available for methadone

  • 10mg
  • 10mg/ml
  • 2.5mg
  • 20mg
  • 40mg
  • 5mg
  • 5mg/ml

Compensation lists for METADON BIOEEL 20mg Bioeel

G10 (C1) - Leukemias, lymphomas and bone marrow aplasia, tumors

Price

Copayment

Patient

110.10 RON

110.10 RON

0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

110.10 RON

110.10 RON

0.00 RON

NHP 11.1 (C2) - Treatment of drug addiction

Price

Copayment

Patient

110.10 RON

110.10 RON

0.00 RON