Indicated for: vertigo; vestibular disorders
Substance: cinnarizine + dimenhydrinate (antihistamine + antiemetic)
ATC: N07CA52 (Nervous system | Antivertigo preparations)
The combination of cinnarizine and dimenhydrinate is used for the treatment and prevention of balance disorders and associated symptoms such as dizziness, vertigo, nausea, and vomiting. It is commonly prescribed for vestibular conditions such as Ménière's disease or vertigo of central or peripheral origin.
Cinnarizine is a calcium channel blocker that improves blood circulation in the inner ear and reduces vestibular overstimulation. Dimenhydrinate is an antihistamine with antiemetic properties that reduces nausea and vomiting by blocking H1 receptors.
This combination is effective in relieving vertigo and nausea symptoms, providing a synergistic effect: cinnarizine addresses the cause of dizziness, while dimenhydrinate alleviates associated symptoms like nausea. It is recommended for both acute episodes and their prevention.
Side effects may include drowsiness, dry mouth, fatigue, headache, or gastrointestinal disturbances. In rare cases, allergic reactions, tremors, or confusion may occur, especially in elderly patients. Patients should avoid alcohol or other sedatives during treatment, as these may enhance drowsiness.
Patients should strictly follow their doctor’s instructions regarding dosage and treatment duration. It is also advised not to drive or operate heavy machinery while using this medication due to the risk of drowsiness.