Leaflet LEPONEX 100mg tablets

Product code:
W63177002
Quantity:
50
Indicated for:
schizophrenia; bipolar disorder
Route of administration:
oral
Substance:
clozapine (antipsychotic)
ATC
N05AH02 — Nervous system | Antipsychotics | Diazepines, oxazepines, thiazepines and oxepines

Precautions:

Driving impairment

This medicine may affect your ability to drive or use machines.

Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Hyperglycemia

This medicine may increase blood sugar.

Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Cardiac risk / QT prolongation / arrhythmias

This medicine may increase the risk of heart rhythm disturbances.

Seizure risk

This medicine may increase the risk of seizures.

Drowsiness / sedation

This medicine may cause drowsiness or reduced alertness.

Clozapine is an atypical antipsychotic used for the treatment of schizophrenia resistant to other therapies and for reducing the risk of suicidal behavior in patients with psychotic disorders. It works by modulating the activity of neurotransmitters in the brain.

The medication is taken orally, as directed by a doctor, usually once or twice daily. It is important for patients to undergo regular blood tests to monitor white blood cell counts due to the risk of agranulocytosis.

Patients should be aware of potential side effects, such as drowsiness, dizziness, or weight gain. It is important to inform the doctor of any unusual symptoms.

Common side effects include drowsiness, dizziness, and weight gain. In rare cases, severe reactions such as agranulocytosis, seizures, or myocarditis may occur. Patients should be informed of these risks before use.

General data about LEPONEX 100mg

Substance:
clozapine
Date of latest medicines list:
01-06-2026
Product code:
W63177002
Concentration:
100mg
Pharmaceutical form:
tablets
Quantity:
50
Product type:
Original
Price:
72.28 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
MYLAN HUNGARY KFT. - UNGARIA
Holder:
MYLAN HEALTHCARE GMBH - GERMANIA
Number:
12019/2019/02
Shelf life:
3 years

Concentrations available for clozapine

  • 100mg
  • 25mg
  • 50mg

Compensation lists for LEPONEX 100mg Mylan

G12 (C1) - Parkinson's disease

Price
72.28 RON
Copayment
72.28 RON
Patient
0.00 RON

G15 (C1) - Mental disorders

Price
72.28 RON
Copayment
72.28 RON
Patient
0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price
72.28 RON
Copayment
72.28 RON
Patient
0.00 RON