Leaflet LANVIS 40mg tablets

Indicated for: cancer

Route of administration: oral

Substance: thioguanine (antineoplastic agent)

ATC: L01BB03 (Antineoplastic and immunomodulating agents | Antimetabolites | Purine analogues)

Precautions:
Fertility warning
Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment
Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling
Cytotoxic / special handling

Handle with special care.

Contraception required
Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding
Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis
Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Thioguanine is an antimetabolite agent used in the treatment of acute leukemia and other hematologic cancers. It works by interfering with DNA and RNA synthesis in cancer cells, thereby inhibiting their growth and division.

The medication is taken orally, usually once daily, as directed by a doctor. The dosage is adjusted based on the patient's weight, clinical condition, and response to treatment.

Patients should be closely monitored to detect potential side effects, such as bone marrow suppression, nausea, or liver toxicity. It is important for patients to inform their doctor of any unusual symptoms.

Common side effects include nausea, vomiting, decreased blood cell counts, and elevated liver enzymes. In rare cases, severe reactions such as hepatotoxicity or serious infections may occur. Patients should be informed of these risks before starting treatment.

General data about LANVIS 40mg

  • Substance: thioguanine
  • Date of latest medicines list: 01-06-2026
  • Product code: W58869001
  • Concentration: 40mg
  • Pharmaceutical form: tablets
  • Quantity: 25
  • Product type: Original
  • Price: 485.65 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: EXCELLA GMBH - GERMANIA
  • Holder: ASPEN PHARMA TRADING LIMITED - IRLANDA
  • Number: 7909/2015/01
  • Shelf life: 5 years

Compensation lists for LANVIS 40mg Aspen

NHP 3 (C2) - NHP oncology

Price

Copayment

Patient

485.65 RON

485.65 RON

0.00 RON