Dose adjustment in hepatic impairment
Dose adjustment may be needed in liver disease.
Leaflet KLION-D 100 100mg / 100mg vaginal tablets
- Product code:
- W01951001
- Quantity:
- 10
- Indicated for:
- bacterial infections
- Route of administration:
- vaginal
- Substance:
- metronidazole + miconazole (nitroimidazole antimicrobial + azole antifungal)
- ATC
- G01AF20 — Genito urinary system and sex hormones | Antiinfectives and antiseptics, excl. combinations with corticosteroids | Imidazole derivatives
Precautions:
Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Anaphylaxis
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Colitis / severe diarrhea
Seek medical advice if severe or persistent diarrhea occurs.
Major drug interactions
This medicine may have important interactions with other medicines.
Pregnancy warning
Use during pregnancy only on medical advice.
Cardiac risk / QT prolongation / arrhythmias
This medicine may increase the risk of heart rhythm disturbances.
The combination of metronidazole and miconazole is used for the treatment of mixed vaginal infections caused by anaerobic bacteria and fungi, such as bacterial vaginosis and vaginal candidiasis. Metronidazole acts as an antibacterial agent, while miconazole is an antifungal.
The medication is administered topically, in the form of vaginal suppositories or cream, usually once daily for 7 days. Common side effects include local irritation, itching, and a burning sensation.
This combination is contraindicated in patients with hypersensitivity to any of the components or in pregnant women during the first trimester. Its use also requires caution to prevent imbalances in vaginal flora.
This medication is an effective option for managing mixed vaginal infections, helping to alleviate symptoms and prevent recurrences.
The medication is administered topically, in the form of vaginal suppositories or cream, usually once daily for 7 days. Common side effects include local irritation, itching, and a burning sensation.
This combination is contraindicated in patients with hypersensitivity to any of the components or in pregnant women during the first trimester. Its use also requires caution to prevent imbalances in vaginal flora.
This medication is an effective option for managing mixed vaginal infections, helping to alleviate symptoms and prevent recurrences.
General data about KLION-D 100 100mg / 100mg
- Substance:
- metronidazole + miconazole
- Date of latest medicines list:
- 01-07-2013
- Product code:
- W01951001
- Concentration:
- 100mg / 100mg
- Pharmaceutical form:
- vaginal tablets
- Quantity:
- 10
- Product type:
- Generic medicine
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.