Indicated for: general anesthesia; procedural sedation
Route of administration: injectable
Substance: ketamine (general anesthetic)
ATC: N01AX03 (Nervous system | Anesthetics, general | Other general anesthetics)
Ketamine is a medication primarily used as a general anesthetic, with analgesic and sedative properties. It is commonly used in surgical and medical procedures, especially in emergency situations, due to its rapid onset and safety in maintaining respiratory and cardiovascular functions.
In lower doses, ketamine is used to treat acute and chronic pain, and it has recently been approved for treatment-resistant depression in the form of a nasal spray (esketamine). It works by blocking NMDA receptors in the brain, which affects pain perception and mood regulation.
Side effects may include hallucinations, confusion, dizziness, increased blood pressure, or a rapid heart rate. Recreationally, ketamine is abused for its dissociative effects, which can lead to addiction and health issues. Its administration must be strictly supervised by qualified medical personnel.