Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Medicine information IRBESARTAN HYDROCHLOROTHIAZIDE ZENTIVA 150mg / 12.5mg film-coated tablets
- Product code:
- W59584002
- Quantity:
- 28
- Indicated for:
- hypertension
- Route of administration:
- oral
- Substance:
- irbesartan + hydrochlorothiazide (angiotensin II receptor blocker+diuretic)
- ATC
- C09DA04 — Cardiovascular system | Angiotensin II receptor blockers (ARBs), combinations | Angiotensin ii receptor blockers (arbs) and diuretics
The combination of irbesartan and hydrochlorothiazide is used to treat essential hypertension in patients who do not respond adequately to monotherapy. Irbesartan is an angiotensin II receptor antagonist that helps relax blood vessels, while hydrochlorothiazide is a diuretic that reduces fluid volume in the body, thereby lowering blood pressure.
The medication is taken orally, usually once daily, as directed by a doctor.
Side effects may include dizziness, fatigue, nausea, or electrolyte imbalances. In rare cases, severe allergic reactions or kidney dysfunction may occur.
Patients should inform their doctor about any other medications they are taking and strictly follow the treatment regimen. Pregnant or breastfeeding women should not use this medication.
The medication is taken orally, usually once daily, as directed by a doctor.
Side effects may include dizziness, fatigue, nausea, or electrolyte imbalances. In rare cases, severe allergic reactions or kidney dysfunction may occur.
Patients should inform their doctor about any other medications they are taking and strictly follow the treatment regimen. Pregnant or breastfeeding women should not use this medication.
General data about IRBESARTAN HYDROCHLOROTHIAZIDE ZENTIVA 150mg / 12.5mg
- Substance:
- irbesartan + hydrochlorothiazide
- Date of latest medicines list:
- 01-10-2026
- Product code:
- W59584002
- Strength:
- 150mg / 12.5mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 28
- Product type:
- Generic medicine
- Price:
- 25.09 RON
- Prescription status:
- P-6L — Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.
Pharmaceutical forms available for irbesartan + hydrochlorothiazide
Strengths available for irbesartan + hydrochlorothiazide
- 150mg/12.5mg
- 300mg/12.5mg
- 300mg/25mg
Official documents
The SmPC text is not displayed because a match to this medicine, strength and pharmaceutical form has not been confirmed.
- Added to database:
- 19/10/2009
- Source record updated:
- 04/08/2026
Warnings:
Contraindicated during pregnancy
Do not use this medicine during pregnancy.
Photosensitivity
Avoid excessive exposure to sunlight or UV radiation.
Hypotension / fall risk
May lower blood pressure and increase the risk of falls.
Major drug interactions
This medicine may have important interactions with other medicines.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Electrolyte disturbances
This medicine may change blood electrolyte levels.
Reimbursement lists for IRBESARTAN HYDROCHLOROTHIAZIDE ZENTIVA 150mg / 12.5mg Aventis
B - Sublist B with 50% discount from the reference price
- Price
- 25.09 RON
- Copayment
- 11.22 RON
- Patient payment
- 13.87 RON