Leaflet IMURAN 50mg film-coated tablets
Indicated for: immunosuppression
Route of administration: oral
Substance: azathioprine (immunosuppressant)
ATC: L04AX01 (Antineoplastic and immunomodulating agents | Immunosuppressants | Other immunosuppressants)
Avoid live vaccines during treatment if contraindicated.
This medicine may increase the risk of infections.
This medicine may have important interactions with other medicines.
This medicine may lower blood cell counts.
Use during breastfeeding only on medical advice.
Use during pregnancy only on medical advice.
A genetic test may be needed before treatment.
Azathioprine is an immunosuppressive agent used in the treatment of autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel diseases (Crohn's disease and ulcerative colitis). It is also used to prevent organ rejection following transplants, particularly kidney transplants.
Azathioprine works by inhibiting purine synthesis, reducing the proliferation of T and B lymphocytes, and suppressing the immune response. It is administered orally or intravenously, with the dose adjusted based on body weight and patient response.
Common side effects include nausea, vomiting, diarrhea, and bone marrow suppression, which can lead to anemia, leukopenia, and thrombocytopenia. In rare cases, severe adverse reactions such as hepatotoxicity, pancreatitis, or an increased risk of infections and malignancies may occur. Regular monitoring of hematological and hepatic parameters is essential during treatment.
Azathioprine is an effective therapeutic option for managing autoimmune diseases and preventing organ rejection, contributing to improved quality of life for patients.
General data about IMURAN 50mg
- Substance: azathioprine
- Date of latest medicines list: 01-06-2026
- Product code: W60846001
- Concentration: 50mg
- Pharmaceutical form: film-coated tablets
- Quantity: 100
- Product type: Original
- Price: 67.06 RON
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Concentrations available for azathioprine
- 100mg
- 25mg
- 50mg
- 75mg
Compensation lists for IMURAN 50mg Aspen
B - Sublist B with 50% discount from the reference price
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67.06 RON
33.53 RON
33.53 RON
G17 (C1) - Major collagenosis (systemic lupus erythematosus, scleroderma)
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67.06 RON
67.06 RON
0.00 RON
G18 (C1) - Rheumatoid arthritis, psoriatic arthropathy, severe chronic psoriasis and juvenile arthritis
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67.06 RON
67.06 RON
0.00 RON
GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)
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67.06 RON
67.06 RON
0.00 RON
NHP 9.4 (C2) - Kidney transplant, combined kidney and pancreas transplant
Price
Copayment
Patient
67.06 RON
67.06 RON
0.00 RON
NHP 9.7 (C2) - Outpatient treatment of transplant patients
Price
Copayment
Patient
67.06 RON
67.06 RON
0.00 RON