Leaflet IMIPENEM/CILASTATIN NORIDEM 500mg / 500mg powder for solution for infusion

Product code:
W71456001
Quantity:
1
Indicated for:
bacterial infections
Route of administration:
infusion
Substance:
imipenem + cilastatin (carbapenem antibiotic + statin lipid-lowering agent)
ATC
J01DH51 — Antiinfectives for systemic use | Other beta-lactam antibacterials | Carbapenems

Precautions:

Dose adjustment in renal impairment

Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Anaphylaxis

Anaphylaxis

Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.

Colitis / severe diarrhea

Colitis / severe diarrhea

Seek medical advice if severe or persistent diarrhea occurs.

Major drug interactions

Major drug interactions

This medicine may have important interactions with other medicines.

Pregnancy warning

Pregnancy warning

Use during pregnancy only on medical advice.

Seizure risk

Seizure risk

This medicine may increase the risk of seizures.

The combination of imipenem and cilastatin is an antibiotic used to treat severe bacterial infections, including respiratory, urinary, abdominal infections, or sepsis. Imipenem is a carbapenem antibiotic, and cilastatin prevents its degradation in the kidneys, enhancing its effectiveness.

The medication is administered via intravenous injection under the supervision of a specialist.

Side effects may include nausea, vomiting, diarrhea, skin rashes, or injection site reactions. In rare cases, severe allergic reactions or seizures may occur.

Patients should inform their doctor about any allergies or other medications they are taking. Pregnant or breastfeeding women should consult a specialist before use.

General data about IMIPENEM/CILASTATIN NORIDEM 500mg / 500mg

Substance:
imipenem + cilastatin
Date of latest medicines list:
01-12-2025
Product code:
W71456001
Concentration:
500mg / 500mg
Pharmaceutical form:
powder for solution for infusion
Quantity:
1
Product type:
Generic medicine
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
DEMO S.A. PHARMACEUTICAL INDUSTRY - GRECIA
Holder:
NORIDEM ENTERPRISES LIMITED - CIPRU
Number:
16281/2025/01
Shelf life:
3 years-after packaging for sale;after reconstituting the solution-it is used immediately

Concentrations available for imipenem + cilastatin

  • 250mg/250mg
  • 500mg/500mg

Combinations with other substances