Indicated for: orthostatic hypotension
Route of administration: oral
Substance: midodrine (vasopressor)
ATC: C01CA17 (Cardiovascular system | Cardiac stimulants excluding cardiac glycosides | Adrenergic and dopaminergic agents)
Midodrine is a sympathomimetic agent used for the treatment of symptomatic orthostatic hypotension. It works by stimulating alpha-adrenergic receptors, leading to increased vascular tone and elevated blood pressure.
The medication is taken orally, usually two or three times daily, with the dose adjusted based on the patient's response. Common side effects include itching, paresthesia, chills, and supine hypertension.
Midodrine is contraindicated in patients with severe hypertension, severe renal impairment, or hypersensitivity to the active substance. Its use also requires careful monitoring to prevent cardiovascular complications.
This medication is an effective option for managing orthostatic hypotension, helping to improve patients' quality of life.