Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Leaflet FLUDEXAM 1.5mg / 5mg modified release tablets
- Product code:
- W60531001
- Quantity:
- 15
- Indicated for:
- hypertension
- Route of administration:
- oral
- Substance:
- indapamide + amlodipine (diuretic+calcium channel blocker)
- ATC
- C08GA02 — Cardiovascular system | Calcium channel blockers | Calcium channel blockers and diuretics
Indapamide + amlodipine treats high blood pressure. The fixed-dose product generally replaces the same doses taken separately in patients whose blood pressure is already controlled; it is not intended for initial dose selection. Indapamide is a thiazide-like diuretic, while amlodipine blocks calcium channels and relaxes blood vessels.
The tablet is usually taken once daily in the morning, as prescribed. The modified-release form must be swallowed whole, not chewed or crushed. Check blood pressure and continue treatment even when feeling well. Kidney function, sodium and potassium may need blood tests, particularly at the start or after treatment changes.
Ankle swelling, headache, flushing, dizziness, tiredness or low blood pressure may occur. Indapamide can lower sodium or potassium, raise uric acid and promote gout or sensitivity to sunlight. Weakness, cramps, confusion or palpitations can signal an imbalance requiring assessment.
Seek emergency help for fainting, breathing difficulty or swelling of the face and tongue. Report kidney or liver disease, gout, pregnancy, breastfeeding and all medicines, particularly lithium and anti-inflammatory painkillers. Avoid grapefruit and grapefruit juice as instructed in the leaflet. Do not add diuretics or potassium supplements without advice.
The tablet is usually taken once daily in the morning, as prescribed. The modified-release form must be swallowed whole, not chewed or crushed. Check blood pressure and continue treatment even when feeling well. Kidney function, sodium and potassium may need blood tests, particularly at the start or after treatment changes.
Ankle swelling, headache, flushing, dizziness, tiredness or low blood pressure may occur. Indapamide can lower sodium or potassium, raise uric acid and promote gout or sensitivity to sunlight. Weakness, cramps, confusion or palpitations can signal an imbalance requiring assessment.
Seek emergency help for fainting, breathing difficulty or swelling of the face and tongue. Report kidney or liver disease, gout, pregnancy, breastfeeding and all medicines, particularly lithium and anti-inflammatory painkillers. Avoid grapefruit and grapefruit juice as instructed in the leaflet. Do not add diuretics or potassium supplements without advice.
General data about FLUDEXAM 1.5mg / 5mg
- Substance:
- indapamide + amlodipine
- Date of latest medicines list:
- 01-07-2014
- Product code:
- W60531001
- Concentration:
- 1.5mg / 5mg
- Pharmaceutical form:
- modified release tablets
- Quantity:
- 15
- Product type:
- Original
- Prescription status:
- P-6L — Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.
Concentrations available for indapamide + amlodipine
- 1.5mg/10mg
- 1.5mg/5mg
Combinations with other substances
Precautions:
Hypotension / fall risk
May lower blood pressure and increase the risk of falls.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Electrolyte disturbances
This medicine may change blood electrolyte levels.