Leaflet DIPHERELINE 22.5mg powder and solvent for prolonged-release suspension for injection

Product code:
W62618001
Quantity:
1
Indicated for:
prostate cancer; breast cancer; endometriosis
Route of administration:
injectable
Substance:
triptorelin (GnRH agonist)
ATC
L02AE04 — Antineoplastic and immunomodulating agents | Hormones and related agents | Gonadotropin releasing hormone analogues
Triptorelin is a synthetic analog of gonadotropin-releasing hormone (GnRH) used in the treatment of hormone-dependent conditions such as prostate cancer, endometriosis, and precocious puberty. It works by inhibiting the secretion of gonadotropins (LH and FSH), leading to decreased testosterone levels in men and estrogen levels in women.

Triptorelin is administered as intramuscular or subcutaneous injections, usually at intervals of 1, 3, or 6 months, depending on the therapeutic indication. It is commonly used in hormone suppression therapy to slow the progression of prostate cancer or to control symptoms of endometriosis.

Common side effects include hot flashes, decreased libido, fatigue, and headaches. In rare cases, allergic reactions or long-term bone density loss may occur. Regular monitoring is essential to evaluate treatment efficacy and manage side effects.

Triptorelin is an effective and well-tolerated medication for managing hormone-dependent conditions, helping to improve patients' quality of life.

General data about DIPHERELINE 22.5mg

Substance:
triptorelin
Date of latest medicines list:
01-06-2026
Product code:
W62618001
Concentration:
22.5mg
Pharmaceutical form:
powder and solvent for prolonged-release suspension for injection
Quantity:
1
Product type:
Original
Price:
2351.07 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
IPSEN PHARMA BIOTECH - FRANTA
Holder:
IPSEN PHARMA - FRANTA
Number:
8689/2016/01
Shelf life:
3 years-after packing for marketing;after reconstitution-se administreaza imediat

Concentrations available for triptorelin

  • 0.1mg
  • 0.1mg/ml
  • 11.25mg
  • 22.5mg
  • 3.75mg

Compensation lists for DIPHERELINE 22.5mg Ipsen

NHP 3 (C2) - NHP oncology

Price
2351.07 RON
Copayment
2351.07 RON
Patient
0.00 RON