Leaflet DIGOXINA ZENTIVA 0.25mg tablets

Product code:
W58535002
Quantity:
25
Indicated for:
heart failure; cardiac arrhythmias
Route of administration:
oral
Substance:
digoxin (antiarrhythmic)
ATC
C01AA05 — Cardiovascular system | Cardiac glycosides | Digitalis glycosides

Precautions:

Dose adjustment in renal impairment

Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Narrow therapeutic index

Narrow therapeutic index

The dose must be followed strictly.

Additional monitoring

Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests

Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Cardiac risk / QT prolongation / arrhythmias

Cardiac risk / QT prolongation / arrhythmias

This medicine may increase the risk of heart rhythm disturbances.

Digoxin is a medication used to treat heart failure and certain types of arrhythmias, such as atrial fibrillation and atrial flutter. It belongs to the class of cardiac glycosides and works by increasing the force of heart contractions (positive inotropic effect) and slowing the heart rate (negative chronotropic effect), thereby improving the efficiency of heart function.

It is available in the form of tablets, oral solution, or injectable solution, with the dosage adjusted based on the patient's condition, kidney function, and serum digoxin levels.

Side effects may include nausea, vomiting, diarrhea, loss of appetite, dizziness, confusion, visual disturbances (such as halos or blurred vision), and arrhythmias. Digoxin toxicity is a serious complication and is more likely to occur in patients with kidney impairment or electrolyte imbalances (such as hypokalemia).

Digoxin is contraindicated in cases of ventricular fibrillation, complete atrioventricular block without a pacemaker, or hypersensitivity to the drug. Patients should be closely monitored, and serum digoxin levels should be checked regularly to prevent toxicity.

General data about DIGOXINA ZENTIVA 0.25mg

Substance:
digoxin
Date of latest medicines list:
01-06-2026
Product code:
W58535002
Concentration:
0.25mg
Pharmaceutical form:
tablets
Quantity:
25
Product type:
Generic medicine
Price:
30.44 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
ZENTIVA S.A. - ROMANIA
Holder:
ZENTIVA S.A. - ROMANIA
Number:
12803/2019/01
Shelf life:
3 years

Pharmaceutical forms available for digoxin

Concentrations available for digoxin

  • 0.05mg/ml
  • 0.25mg
  • 0.25mg/ml
  • 0.5mg/2ml
  • 0.5mg/ml

Compensation lists for DIGOXINA ZENTIVA 0.25mg Zentiva

A - Sublist A with 90% discount from the reference price

Price
30.44 RON
Copayment
27.40 RON
Patient
3.04 RON

G1 (C1) - Chronic heart failure (NYHA class III or IV)

Price
30.44 RON
Copayment
30.44 RON
Patient
0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price
30.44 RON
Copayment
30.44 RON
Patient
0.00 RON