Indicated for: hypertension
Route of administration: oral
Substance: valsartan + hydrochlorothiazide (angiotensin II receptor blocker + diuretic)
ATC: C09CA03 (Cardiovascular system | Angiotensin II receptor blockers (arbs), plain | Angiotensin ii receptor blockers (arbs), plain)
Dose adjustment may be needed in kidney disease.
Do not use this medicine during pregnancy.
Avoid excessive exposure to sunlight or UV radiation.
May lower blood pressure and increase the risk of falls.
This medicine may have important interactions with other medicines.
Periodic laboratory tests may be required during treatment.
This medicine may change blood electrolyte levels.
The combination of valsartan and hydrochlorothiazide is used for the treatment of hypertension, particularly in patients who do not respond adequately to monotherapy. Valsartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels and lowers blood pressure by blocking the effects of angiotensin II. Hydrochlorothiazide is a thiazide diuretic that helps eliminate excess salt and water from the body, thereby reducing blood pressure.
This combination is administered orally, usually once daily, and the dosage is adjusted based on the patient's response and blood pressure levels. It is important for patients to adhere to the treatment and regularly monitor their blood pressure.
Common side effects include dizziness, headaches, fatigue, and hypokalemia. In rare cases, severe adverse reactions such as renal failure, hyponatremia, or allergic reactions may occur.
The combination of valsartan and hydrochlorothiazide provides an effective option for managing hypertension, helping to reduce the risk of cardiovascular complications such as myocardial infarction or stroke.